Rompun: Precisely-determined dosages ensure reliability – whatever the animal.
Pharmacokinetics: how Rompun is administered.
- intravenously (IV)
- intramuscularly (IM) (excellent tolerability thanks to xylazine’s potent action as a local anaesthetic)
- subcutaneously (SC) (very useful for cats)
- intraperitoneally (IP) especially in small mammals and exotic animals
- epidurally in cattle and occasionally in other species.
Absorption: is very rapid, both after intramuscular and intravenous administration. The onset of action depends on the species and route of administration: the drug takes effect immediately in cattle, dogs and cats, within 3 to 5 minutes in horses after intravenous administration, and within 10 to 15 minutes after intramuscular administration.
Distribution: after several minutes, Rompun is distributed to virtually all organs of the body, particularly throughout the central nervous system.
Metabolism: is extensive, producing around twenty metabolites. Rompun is eliminated predominantly in the urine in the form of inactive metabolites.
Rompun’s major advantage lies in the timing of the onset and cessation of its three important anaesthetic effects:

The muscle relaxant effect ceases before the sedative effect, so that when the animal recovers consciousness, it can rise with no risk of accidents.
Rompun’s distinguishing features are its rapid onset of action, quick restoration of normal body functions and a calm recovery of consciousness.
